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Preparation of Nanocrystals for Insoluble Drugs by Top-Down Nanotechnology with Improved Solubility and Bioavailability

Midazolam is a rapidly effective benzodiazepine drug that is widely used as a sedative worldwide. Due to its poor solubility in a neutral aqueous solution, the clinical use of midazolam is significantly limited. As one of the most promising formulations for poorly water-soluble drugs, nanocrystals h...

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Detalles Bibliográficos
Autores principales:	Zhang, Xun, Li, Zhiguo, Gao, Jing, Wang, Zengming, Gao, Xiang, Liu, Nan, Li, Meng, Zhang, Hui, Zheng, Aiping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7179175/ https://www.ncbi.nlm.nih.gov/pubmed/32121076 http://dx.doi.org/10.3390/molecules25051080

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