Cargando…

Metabolite Profiling and Distribution of Militarine in Rats Using UPLC-Q-TOF-MS/MS

Militarine, a natural glucosyloxybenzyl 2-isobutylmalate, isolated from Bletilla striata, was reported with a prominent neuroprotective effect recently. The limited information on the metabolism of militarine impedes comprehension of its biological actions and pharmacology. This study aimed to inves...

Descripción completa

Detalles Bibliográficos
Autores principales:	Li, Limin, Hao, Bin, Zhang, Yulong, Ji, Shen, Chou, Guixin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7179186/ https://www.ncbi.nlm.nih.gov/pubmed/32121087 http://dx.doi.org/10.3390/molecules25051082

Ejemplares similares

Identification of Sanguinarine Metabolites in Rats Using UPLC-Q-TOF-MS/MS
por: Liu, Mengting, et al.
Publicado: (2023)

Antihepatotoxic Effect and Metabolite Profiling of Panicum turgidum Extract via UPLC-qTOF-MS
por: Farag, Mohamed A., et al.
Publicado: (2016)

Chemical profiles and metabolite study of raw and processed Cistanche deserticola in rats by UPLC-Q-TOF-MS(E)
por: Li, Zhe, et al.
Publicado: (2021)

A Validated HPLC-MS/MS Method for Simultaneous Determination of Militarine and Its Three Metabolites in Rat Plasma: Application to a Pharmacokinetic Study
por: Sun, Hui-Yuan, et al.
Publicado: (2019)

Secondary Metabolite Profiling of Curcuma Species Grown at Different Locations Using GC/TOF and UPLC/Q-TOF MS
por: Lee, Jueun, et al.
Publicado: (2014)

Simultaneous Analysis of Iridoid Glycosides and Anthraquinones in Morinda officinalis Using UPLC-QqQ-MS/MS and UPLC-Q/TOF-MS(E)
por: Zhao, Xiangsheng, et al.
Publicado: (2018)

Profiling and Pharmacokinetic Studies of Alkaloids in Rats After Oral Administration of Zanthoxylum nitidum Decoction by UPLC-Q-TOF-MS/MS and HPLC-MS/MS
por: Huang, Aihua, et al.
Publicado: (2019)

Quality Evaluation of Tricholoma matsutake Based on the Nucleic Acid Compounds by UPLC-TOF/MS and UPLC-QqQ/MS
por: Xue, Ying, et al.
Publicado: (2018)

Serum biomarkers of the calcium-deficient rats identified by metabolomics based on UPLC/Q-TOF MS/MS
por: Meng, Fanyu, et al.
Publicado: (2020)

Systematic characterization of metabolic profiles of ingenol in rats by UPLC-Q/TOF-MS and NMR in combination with microbial biotransformation
por: Xiao, Si-Jia, et al.
Publicado: (2021)

Sphingolipidomic Profiling of Rat Serum by UPLC-Q-TOF-MS: Application to Rheumatoid Arthritis Study
por: Qu, Fanghui, et al.
Publicado: (2018)

Comprehensive Metabolic Profiling of Euphorbiasteroid in Rats by Integrating UPLC-Q/TOF-MS and NMR as Well as Microbial Biotransformation
por: Xiao, Sijia, et al.
Publicado: (2022)

Metabolite Profiling of Dihydroartemisinin in Blood of Plasmodium-Infected and Healthy Mice Using UPLC-Q-TOF-MS(E)
por: Zhao, Yifan, et al.
Publicado: (2021)

Identification of prototype compounds and their metabolites in rats’ serum from Xuefu Zhuyu Decoction by UPLC-Q-TOF/MS
por: Zhang, Xiaoyu, et al.
Publicado: (2022)

A Comprehensive Study to Identify Major Metabolites of an Amoxicillin–Sulbactam Hybrid Molecule in Rats and Its Metabolic Pathway Using UPLC-Q-TOF-MS/MS
por: Zhao, Fei-Ke, et al.
Publicado: (2022)

Chemical Profiling of Xueshuan Xinmaining Tablet by HPLC and UPLC-ESI-Q-TOF/MS
por: Han, Ya-Xin, et al.
Publicado: (2018)

Metabolite Profiling of Meridianin C In Vivo of Rat by UHPLC/Q-TOF MS
por: Zhang, Guozhe, et al.
Publicado: (2021)

Profiling and Distribution of Metabolites of Procyanidin B2 in Mice by UPLC-DAD-ESI-IT-TOF-MS(n) Technique
por: Xiao, Ying, et al.
Publicado: (2017)

Metabolite Profiling of Rambutan (Nephelium lappaceum L.) Seeds Using UPLC-qTOF-MS/MS and Senomorphic Effects in Aged Human Dermal Fibroblasts
por: Lee, Yae Rin, et al.
Publicado: (2020)

Potential serum biomarkers and metabonomic profiling of serum in ischemic stroke patients using UPLC/Q-TOF MS/MS
por: Sun, Hongxue, et al.
Publicado: (2017)

Qualitative and Quantitative Analysis of the Major Constituents in Shexiang Tongxin Dropping Pill by HPLC-Q-TOF-MS/MS and UPLC-QqQ-MS/MS
por: Chen, Daxin, et al.
Publicado: (2015)

Identification of absorbed constituents and evaluation of the pharmacokinetics of main compounds after oral administration of yindanxinnaotong by UPLC-Q-TOF-MS and UPLC-QqQ-MS
por: Gong, Leilei, et al.
Publicado: (2018)

UPLC-ESI-Q-TOF-MS-Based Metabolite Profiling, Antioxidant and Anti-Inflammatory Properties of Different Organ Extracts of Abeliophyllum distichum
por: Yoo, Tong-Kewn, et al.
Publicado: (2021)

Effect of Wuzi Yanzong prescription on oligoasthenozoospermia rats based on UPLC-Q-TOF-MS metabolomics
por: Chen, Zhimin, et al.
Publicado: (2022)

Metabolite Profiling of 14 Wuyi Rock Tea Cultivars Using UPLC-QTOF MS and UPLC-QqQ MS Combined with Chemometrics
por: Chen, Si, et al.
Publicado: (2018)

Identification and Pharmacokinetic Studies on Complanatuside and Its Major Metabolites in Rats by UHPLC-Q-TOF-MS/MS and LC-MS/MS
por: Yao, Yu-Feng, et al.
Publicado: (2018)

Integrated UPLC-Q-TOF-MS/MS and Network Pharmacology Approach to Investigating the Metabolic Profile of Marein of Coreopsis tinctoria Nutt.
por: Liu, Jing, et al.
Publicado: (2022)

Analysis of the Constituents in Rat Serum after Oral Administration of Fufang Zhenzhu Tiaozhi Capsule by UPLC–Q–TOF–MS/MS
por: Zhong, Xunlong, et al.
Publicado: (2011)

Metabolic profiling and pharmacokinetic studies of Baihu-Guizhi decoction in rats by UFLC-Q-TOF–MS/MS and UHPLC-Q-TRAP-MS/MS
por: He, Yan, et al.
Publicado: (2022)

UPLC-Q-TOF-MS Study of the Mechanism of THSWD for Breast Cancer Treatment
por: Duan, Xianchun, et al.
Publicado: (2020)

Identification of metabolites of liquiritin in rats by UHPLC-Q-TOF-MS/MS: metabolic profiling and pathway comparison in vitro and in vivo
por: Zhang, Xia, et al.
Publicado: (2018)

UPLC-Q-TOF-MS profiling of the hippocampus reveals metabolite biomarkers for the impact of Dl-3-n-butylphthalide on the lipopolysaccharide-induced rat model of depression
por: Geng, Chunmei, et al.
Publicado: (2019)

UPLC-Q-TOF/MS based metabolomic profiling of serum and urine of hyperlipidemic rats induced by high fat diet
por: Wu, Qiong, et al.
Publicado: (2014)

Changes of myocardial lipidomics profiling in a rat model of diabetic cardiomyopathy using UPLC/Q-TOF/MS analysis
por: Dong, Shifen, et al.
Publicado: (2017)

Metabolomics Study of Different Germplasm Resources for Three Polygonatum Species Using UPLC-Q-TOF-MS/MS
por: Wang, Shiqiang, et al.
Publicado: (2022)

UPLC-qTOF-MS Phytochemical Profile and Antiulcer Potential of Cyperus conglomeratus Rottb. Alcoholic Extract
por: Elshamy, Abdelsamed I., et al.
Publicado: (2020)

Plasma metabolic profiling analysis of Cortex Periplocae-induced cardiotoxicity based on UPLC/Q-TOF-MS
por: Li, Yubo, et al.
Publicado: (2018)

UPLC-Q-TOF-MS/MS Analysis for Steaming Times-dependent Profiling of Steamed Panax quinquefolius and Its Ginsenosides Transformations Induced by Repetitious Steaming
por: Sun, Bai-Shen, et al.
Publicado: (2012)

The Effect of Temperature on Pressurised Hot Water Extraction of Pharmacologically Important Metabolites as Analysed by UPLC-qTOF-MS and PCA
por: Khoza, B. S., et al.
Publicado: (2014)

Assessing the quality of Smilacis Glabrae Rhizoma (Tufuling) by colormetrics and UPLC-Q-TOF-MS
por: He, Xicheng, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_obju3e6qnbnf18ffk6eon6rklc