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Surface Treatment of Acetabular Cups with a Direct Deposition of a Composite Nanostructured Layer Using a High Electrostatic Field

A composite nanofibrous layer containing collagen and hydroxyapatite was deposited on selected surface areas of titanium acetabular cups. The layer was deposited on the irregular surface of these 3D objects using a specially developed electrospinning system designed to ensure the stability of the sp...

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Autores principales: Pokorný, Marek, Suchý, Tomáš, Kotzianová, Adéla, Klemeš, Jan, Denk, František, Šupová, Monika, Sucharda, Zbyněk, Sedláček, Radek, Horný, Lukáš, Králík, Vlastimil, Velebný, Vladimír, Čejka, Zdeněk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7179214/
https://www.ncbi.nlm.nih.gov/pubmed/32150982
http://dx.doi.org/10.3390/molecules25051173
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author Pokorný, Marek
Suchý, Tomáš
Kotzianová, Adéla
Klemeš, Jan
Denk, František
Šupová, Monika
Sucharda, Zbyněk
Sedláček, Radek
Horný, Lukáš
Králík, Vlastimil
Velebný, Vladimír
Čejka, Zdeněk
author_facet Pokorný, Marek
Suchý, Tomáš
Kotzianová, Adéla
Klemeš, Jan
Denk, František
Šupová, Monika
Sucharda, Zbyněk
Sedláček, Radek
Horný, Lukáš
Králík, Vlastimil
Velebný, Vladimír
Čejka, Zdeněk
author_sort Pokorný, Marek
collection PubMed
description A composite nanofibrous layer containing collagen and hydroxyapatite was deposited on selected surface areas of titanium acetabular cups. The layer was deposited on the irregular surface of these 3D objects using a specially developed electrospinning system designed to ensure the stability of the spinning process and to produce a layer approximately 100 micrometers thick with an adequate thickness uniformity. It was verified that the layer had the intended nanostructured morphology throughout its entire thickness and that the prepared layer sufficiently adhered to the smooth surface of the model titanium implants even after all the post-deposition sterilization and stabilization treatments were performed. The resulting layers had an average thickness of (110 ± 30) micrometers and an average fiber diameter of (170 ± 49) nanometers. They were produced using a relatively simple and cost-effective technology and yet they were verifiably biocompatible and structurally stable. Collagen- and hydroxyapatite-based composite nanostructured surface modifications represent promising surface treatment options for metal implants.
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spelling pubmed-71792142020-04-28 Surface Treatment of Acetabular Cups with a Direct Deposition of a Composite Nanostructured Layer Using a High Electrostatic Field Pokorný, Marek Suchý, Tomáš Kotzianová, Adéla Klemeš, Jan Denk, František Šupová, Monika Sucharda, Zbyněk Sedláček, Radek Horný, Lukáš Králík, Vlastimil Velebný, Vladimír Čejka, Zdeněk Molecules Article A composite nanofibrous layer containing collagen and hydroxyapatite was deposited on selected surface areas of titanium acetabular cups. The layer was deposited on the irregular surface of these 3D objects using a specially developed electrospinning system designed to ensure the stability of the spinning process and to produce a layer approximately 100 micrometers thick with an adequate thickness uniformity. It was verified that the layer had the intended nanostructured morphology throughout its entire thickness and that the prepared layer sufficiently adhered to the smooth surface of the model titanium implants even after all the post-deposition sterilization and stabilization treatments were performed. The resulting layers had an average thickness of (110 ± 30) micrometers and an average fiber diameter of (170 ± 49) nanometers. They were produced using a relatively simple and cost-effective technology and yet they were verifiably biocompatible and structurally stable. Collagen- and hydroxyapatite-based composite nanostructured surface modifications represent promising surface treatment options for metal implants. MDPI 2020-03-05 /pmc/articles/PMC7179214/ /pubmed/32150982 http://dx.doi.org/10.3390/molecules25051173 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Pokorný, Marek
Suchý, Tomáš
Kotzianová, Adéla
Klemeš, Jan
Denk, František
Šupová, Monika
Sucharda, Zbyněk
Sedláček, Radek
Horný, Lukáš
Králík, Vlastimil
Velebný, Vladimír
Čejka, Zdeněk
Surface Treatment of Acetabular Cups with a Direct Deposition of a Composite Nanostructured Layer Using a High Electrostatic Field
title Surface Treatment of Acetabular Cups with a Direct Deposition of a Composite Nanostructured Layer Using a High Electrostatic Field
title_full Surface Treatment of Acetabular Cups with a Direct Deposition of a Composite Nanostructured Layer Using a High Electrostatic Field
title_fullStr Surface Treatment of Acetabular Cups with a Direct Deposition of a Composite Nanostructured Layer Using a High Electrostatic Field
title_full_unstemmed Surface Treatment of Acetabular Cups with a Direct Deposition of a Composite Nanostructured Layer Using a High Electrostatic Field
title_short Surface Treatment of Acetabular Cups with a Direct Deposition of a Composite Nanostructured Layer Using a High Electrostatic Field
title_sort surface treatment of acetabular cups with a direct deposition of a composite nanostructured layer using a high electrostatic field
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7179214/
https://www.ncbi.nlm.nih.gov/pubmed/32150982
http://dx.doi.org/10.3390/molecules25051173
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