Direct Dehydrative Glycosylation Catalyzed by Diphenylammonium Triflate

Methods for direct dehydrative glycosylations of carbohydrate hemiacetals catalyzed by diphenylammonium triflate under microwave irradiation are described. Both armed and disarmed glycosyl-C1-hemiacetal donors were efficiently glycosylated in moderate to excellent yields without the need for any dry...

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Detalles Bibliográficos
Autores principales: Hsu, Mei-Yuan, Lam, Sarah, Wu, Chia-Hui, Lin, Mei-Huei, Lin, Su-Ching, Wang, Cheng-Chung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7179217/
https://www.ncbi.nlm.nih.gov/pubmed/32131396
http://dx.doi.org/10.3390/molecules25051103
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author Hsu, Mei-Yuan
Lam, Sarah
Wu, Chia-Hui
Lin, Mei-Huei
Lin, Su-Ching
Wang, Cheng-Chung
author_facet Hsu, Mei-Yuan
Lam, Sarah
Wu, Chia-Hui
Lin, Mei-Huei
Lin, Su-Ching
Wang, Cheng-Chung
author_sort Hsu, Mei-Yuan
collection PubMed
description Methods for direct dehydrative glycosylations of carbohydrate hemiacetals catalyzed by diphenylammonium triflate under microwave irradiation are described. Both armed and disarmed glycosyl-C1-hemiacetal donors were efficiently glycosylated in moderate to excellent yields without the need for any drying agents and stoichiometric additives. This method has been successfully applied to a solid-phase glycosylation.
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spelling pubmed-71792172020-04-28 Direct Dehydrative Glycosylation Catalyzed by Diphenylammonium Triflate Hsu, Mei-Yuan Lam, Sarah Wu, Chia-Hui Lin, Mei-Huei Lin, Su-Ching Wang, Cheng-Chung Molecules Communication Methods for direct dehydrative glycosylations of carbohydrate hemiacetals catalyzed by diphenylammonium triflate under microwave irradiation are described. Both armed and disarmed glycosyl-C1-hemiacetal donors were efficiently glycosylated in moderate to excellent yields without the need for any drying agents and stoichiometric additives. This method has been successfully applied to a solid-phase glycosylation. MDPI 2020-03-02 /pmc/articles/PMC7179217/ /pubmed/32131396 http://dx.doi.org/10.3390/molecules25051103 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Communication
Hsu, Mei-Yuan
Lam, Sarah
Wu, Chia-Hui
Lin, Mei-Huei
Lin, Su-Ching
Wang, Cheng-Chung
Direct Dehydrative Glycosylation Catalyzed by Diphenylammonium Triflate
title Direct Dehydrative Glycosylation Catalyzed by Diphenylammonium Triflate
title_full Direct Dehydrative Glycosylation Catalyzed by Diphenylammonium Triflate
title_fullStr Direct Dehydrative Glycosylation Catalyzed by Diphenylammonium Triflate
title_full_unstemmed Direct Dehydrative Glycosylation Catalyzed by Diphenylammonium Triflate
title_short Direct Dehydrative Glycosylation Catalyzed by Diphenylammonium Triflate
title_sort direct dehydrative glycosylation catalyzed by diphenylammonium triflate
topic Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7179217/
https://www.ncbi.nlm.nih.gov/pubmed/32131396
http://dx.doi.org/10.3390/molecules25051103
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