Activation of Heme Oxygenase Expression by Cobalt Protoporphyrin Treatment Prevents Pneumonic Plague Caused by Inhalation of Yersinia pestis

Pneumonic plague, caused by the Gram-negative bacteria Yersinia pestis, is an invasive, rapidly progressing disease with poor survival rates. Following inhalation of Y. pestis, bacterial invasion of the lungs and a tissue-damaging inflammatory response allows vascular spread of the infection. Conseq...

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Detalles Bibliográficos
Autores principales: Willix, Joshua L., Stockton, Jacob L., Olson, Rachel M., Anderson, Paul E., Anderson, Deborah M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Experimental Therapeutics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7179272/
https://www.ncbi.nlm.nih.gov/pubmed/32015027
http://dx.doi.org/10.1128/AAC.01819-19

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