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Memantine increases NMDA receptor level in the prefrontal cortex but fails to reverse apomorphine-induced conditioned place preference in rats

Studies have shown that inflammation and neurodegeneration may accompany the development of addiction to apomorphine and that the glutamate NMDA receptor antagonist, memantine, may be neuroprotective. The similarity between apomorphine and dopamine with regard to their chemical, pharmacological and...

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Detalles Bibliográficos
Autores principales: Ndlazi, Ziphozethu, Abboussi, Oualid, Mabandla, Musa, Daniels, Willie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AIMS Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7179335/
https://www.ncbi.nlm.nih.gov/pubmed/32341962
http://dx.doi.org/10.3934/Neuroscience.2018.4.211