Redox-Sensitive and Hyaluronic Acid-Functionalized Nanoparticles for Improving Breast Cancer Treatment by Cytoplasmic 17α-Methyltestosterone Delivery

Novel reduction-responsive hyaluronic acid–chitosan–lipoic acid nanoparticles (HACSLA-NPs) were designed and synthesized for effective treatment of breast cancer by targeting Cluster of Differentiation 44 (CD44)-overexpressing cells and reduction-triggered 17α-Methyltestosterone (MT) release for sys...

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Detalles Bibliográficos
Autores principales: Rezaei, Somayeh, Kashanian, Soheila, Bahrami, Yadollah, Cruz, Luis J., Motiei, Marjan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7179432/
https://www.ncbi.nlm.nih.gov/pubmed/32151062
http://dx.doi.org/10.3390/molecules25051181

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7179432/
https://www.ncbi.nlm.nih.gov/pubmed/32151062
http://dx.doi.org/10.3390/molecules25051181

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