An Enzymatic Flow-Based Preparative Route to Vidarabine

The bi-enzymatic synthesis of the antiviral drug vidarabine (arabinosyladenine, ara-A), catalyzed by uridine phosphorylase from Clostridium perfringens (CpUP) and a purine nucleoside phosphorylase from Aeromonas hydrophila (AhPNP), was re-designed under continuous-flow conditions. Glyoxyl–agarose an...

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Detalles Bibliográficos
Autores principales: Tamborini, Lucia, Previtali, Clelia, Annunziata, Francesca, Bavaro, Teodora, Terreni, Marco, Calleri, Enrica, Rinaldi, Francesca, Pinto, Andrea, Speranza, Giovanna, Ubiali, Daniela, Conti, Paola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7179437/
https://www.ncbi.nlm.nih.gov/pubmed/32182773
http://dx.doi.org/10.3390/molecules25051223

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7179437/
https://www.ncbi.nlm.nih.gov/pubmed/32182773
http://dx.doi.org/10.3390/molecules25051223

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