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A Second Look at the Crystal Structures of Drosophila melanogaster Acetylcholinesterase in Complex with Tacrine Derivatives Provides Insights Concerning Catalytic Intermediates and the Design of Specific Insecticides

Over recent decades, crystallographic software for data processing and structure refinement has improved dramatically, resulting in more accurate and detailed crystal structures. It is, therefore, sometimes valuable to have a second look at “old” diffraction data, especially when earlier interpretat...

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Detalles Bibliográficos
Autores principales: Nachon, Florian, Rosenberry, Terrone L., Silman, Israel, Sussman, Joel L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7179448/
https://www.ncbi.nlm.nih.gov/pubmed/32155891
http://dx.doi.org/10.3390/molecules25051198

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