Cargando…

Emerging Role of the Macrophage Migration Inhibitory Factor Family of Cytokines in Neuroblastoma. Pathogenic Effectors and Novel Therapeutic Targets?

Neuroblastoma (NB) is the most frequent extracranial pediatric tumor. Despite the current available multiple therapeutic options, the prognosis for high-risk NB patients remains unsatisfactory and makes the disease a clear unmet medical need. Thus, more tailored therapeutic approaches are warranted...

Descripción completa

Detalles Bibliográficos
Autores principales:	Cavalli, Eugenio, Ciurleo, Rosella, Petralia, Maria Cristina, Fagone, Paolo, Bella, Rita, Mangano, Katia, Nicoletti, Ferdinando, Bramanti, Placido, Basile, Maria Sofia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7179464/ https://www.ncbi.nlm.nih.gov/pubmed/32155795 http://dx.doi.org/10.3390/molecules25051194

Ejemplares similares

Profiling of inhibitory immune checkpoints in glioblastoma: Potential pathogenetic players
por: Lombardo, Salvo Danilo, et al.
Publicado: (2020)

Overexpression of Macrophage Migration Inhibitory Factor and Its Homologue D-Dopachrome Tautomerase as Negative Prognostic Factor in Neuroblastoma
por: Cavalli, Eugenio, et al.
Publicado: (2019)

Cognitive Decline in Rheumatoid Arthritis: Insight into the Molecular Pathogenetic Mechanisms
por: Basile, Maria Sofia, et al.
Publicado: (2021)

Meta-Analysis of Transcriptomic Data of Dorsolateral Prefrontal Cortex and of Peripheral Blood Mononuclear Cells Identifies Altered Pathways in Schizophrenia
por: Petralia, Maria Cristina, et al.
Publicado: (2020)

Upregulated Expression of Macrophage Migration Inhibitory Factor, Its Analogue D-Dopachrome Tautomerase, and the CD44 Receptor in Peripheral CD4 T Cells from Clinically Isolated Syndrome Patients with Rapid Conversion to Clinical Defined Multiple Sclerosis
por: Cavalli, Eugenio, et al.
Publicado: (2019)

Transcriptomic Data Analysis Reveals a Down-Expression of Galectin-8 in Schizophrenia Hippocampus
por: Petralia, Maria Cristina, et al.
Publicado: (2021)

A Network Medicine Approach for Drug Repurposing in Duchenne Muscular Dystrophy
por: Lombardo, Salvo Danilo, et al.
Publicado: (2021)

The Role of Macrophages in Neuroinflammatory and Neurodegenerative Pathways of Alzheimer’s Disease, Amyotrophic Lateral Sclerosis, and Multiple Sclerosis: Pathogenetic Cellular Effectors and Potential Therapeutic Targets
por: Mammana, Santa, et al.
Publicado: (2018)

The Dichotomic Role of Macrophage Migration Inhibitory Factor in Neurodegeneration
por: Basile, Maria Sofia, et al.
Publicado: (2020)

Pathogenic role for macrophage migration inhibitory factor in glioblastoma and its targeting with specific inhibitors as novel tailored therapeutic approach
por: Mangano, Katia, et al.
Publicado: (2018)

Effects of Combined Admistration of Imatinib and Sorafenib in a Murine Model of Liver Fibrosis
por: Pesce, Antonio, et al.
Publicado: (2020)

Retrospective follow-up analysis of the transcriptomic patterns of cytokines, cytokine receptors and chemokines at preconception and during pregnancy, in women with post-partum depression
por: Petralia, Maria Cristina, et al.
Publicado: (2019)

Preclinical evaluation of the PI3K/Akt/mTOR pathway in animal models of multiple sclerosis
por: Mammana, Santa, et al.
Publicado: (2018)

Transcriptomic Analysis Reveals Involvement of the Macrophage Migration Inhibitory Factor Gene Network in Duchenne Muscular Dystrophy
por: Lombardo, Salvo Danilo, et al.
Publicado: (2019)

Transcriptomic analysis reveals moderate modulation of macrophage migration inhibitory factor superfamily genes in alcohol use disorders
por: Petralia, Maria Cristina, et al.
Publicado: (2020)

Transcriptomic analysis of COVID-19 lungs and bronchoalveolar lavage fluid samples reveals predominant B cell activation responses to infection
por: Cavalli, Eugenio, et al.
Publicado: (2020)

Prediction of PD-L1 Expression in Neuroblastoma via Computational Modeling
por: Lombardo, Salvo Danilo, et al.
Publicado: (2019)

Overexpression of macrophage migration inhibitory factor and functionally-related genes, D-DT, CD74, CD44, CXCR2 and CXCR4, in glioblastoma
por: Presti, Mario, et al.
Publicado: (2018)

Entangling COVID-19 associated thrombosis into a secondary antiphospholipid antibody syndrome: Diagnostic and therapeutic perspectives (Review)
por: Cavalli, Eugenio, et al.
Publicado: (2020)

Transcriptomic Analysis Reveals Abnormal Expression of Prion Disease Gene Pathway in Brains from Patients with Autism Spectrum Disorders
por: Lombardo, Salvo Danilo, et al.
Publicado: (2020)

The Role of Macrophage Migration Inhibitory Factor in Alzheimer′s Disease: Conventionally Pathogenetic or Unconventionally Protective?
por: Petralia, Maria Cristina, et al.
Publicado: (2020)

Upregulation of IL-1 Receptor Antagonist in a Mouse Model of Migraine
por: Lombardo, Salvo Danilo, et al.
Publicado: (2019)

Identification of CD4(+) T cell biomarkers for predicting the response of patients with relapsing-remitting multiple sclerosis to natalizumab treatment
por: Fagone, Paolo, et al.
Publicado: (2019)

Impaired Expression of Tetraspanin 32 (TSPAN32) in Memory T Cells of Patients with Multiple Sclerosis
por: Basile, Maria Sofia, et al.
Publicado: (2020)

Modulation of Tetraspanin 32 (TSPAN32) Expression in T Cell-Mediated Immune Responses and in Multiple Sclerosis
por: Lombardo, Salvo Danilo, et al.
Publicado: (2019)

Transcriptional landscape of SARS-CoV-2 infection dismantles pathogenic pathways activated by the virus, proposes unique sex-specific differences and predicts tailored therapeutic strategies
por: Fagone, Paolo, et al.
Publicado: (2020)

Exploratory Analysis of iPSCS-Derived Neuronal Cells as Predictors of Diagnosis and Treatment of Alzheimer Disease
por: Cavalli, Eugenio, et al.
Publicado: (2020)

Emerging Neurological and Psychobiological Aspects of COVID-19 Infection
por: Tancheva, Lyubka, et al.
Publicado: (2020)

Macrophage Migration Inhibitory Factor (MIF) and Its Homologue D-Dopachrome Tautomerase (DDT) Inversely Correlate with Inflammation in Discoid Lupus Erythematosus
por: Caltabiano, Rosario, et al.
Publicado: (2021)

Past, Present and (Foreseeable) Future of Biological Anti-TNF Alpha Therapy
por: Leone, Gian Marco, et al.
Publicado: (2023)

Characterization of Altered Molecular Pathways in the Entorhinal Cortex of Alzheimer’s Disease Patients and In Silico Prediction of Potential Repurposable Drugs
por: Fagone, Paolo, et al.
Publicado: (2022)

Gene Co-Expression Network Modular Analysis Reveals Altered Immune Mechanisms in HIV-HAND
por: Petralia, Maria Cristina, et al.
Publicado: (2022)

Transcriptional upregulation of galectin-3 in multiple sclerosis
por: Mangano, Katia, et al.
Publicado: (2023)

Computational Analysis of Pathogenetic Pathways in Alzheimer’s Disease and Prediction of Potential Therapeutic Drugs
por: Petralia, Maria Cristina, et al.
Publicado: (2022)

Effects of Treatment with the Hypomethylating Agent 5-aza-2′-deoxycytidine in Murine Type II Collagen-Induced Arthritis
por: Petralia, Maria Cristina, et al.
Publicado: (2019)

Discovering common pathogenetic processes between COVID-19 and diabetes mellitus by differential gene expression pattern analysis
por: Rahman, Md Rezanur, et al.
Publicado: (2021)

Comprehensive Analysis of RNA-Seq Gene Expression Profiling of Brain Transcriptomes Reveals Novel Genes, Regulators, and Pathways in Autism Spectrum Disorder
por: Rahman, Md Rezanur, et al.
Publicado: (2020)

The H(2)S Donor GYY4137 Stimulates Reactive Oxygen Species Generation in BV2 Cells While Suppressing the Secretion of TNF and Nitric Oxide
por: Lazarević, Milica, et al.
Publicado: (2018)

The neuropathic pain: An overview of the current treatment and future therapeutic approaches
por: Cavalli, Eugenio, et al.
Publicado: (2019)

Identification of Common Pathogenetic Processes between Schizophrenia and Diabetes Mellitus by Systems Biology Analysis
por: Rahman, Md Rezanur, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_qas5vbm95hbd7cjor2rpjjo5vf