A Novel Inhaled Dry-Powder Formulation of Ribavirin Allows for Efficient Lung Delivery in Healthy Participants and Those with Chronic Obstructive Pulmonary Disease in a Phase 1 Study

Chronic obstructive pulmonary disease (COPD) is an inflammatory lung condition, causing progressive decline in lung function leading to premature death. Acute exacerbations in COPD patients are predominantly associated with respiratory viruses. Ribavirin is a generic broad-spectrum antiviral agent t...

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Detalles Bibliográficos
Autores principales: Dumont, Etienne F., Oliver, Amanda J., Ioannou, Chris, Billiard, Julia, Dennison, Jeremy, van den Berg, Frans, Yang, Shuying, Chandrasekaran, Vijayalakshmi, Young, Graeme C., Lahiry, Anirban, Starbuck, David C., Harrell, Andrew W., Georgiou, Alex, Hopchet, Nathalie, Gillies, Andy, Baker, Stephen J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Antiviral Agents
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7179635/
https://www.ncbi.nlm.nih.gov/pubmed/32071044
http://dx.doi.org/10.1128/AAC.02267-19

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