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OPA1-Exon4b Binds to mtDNA D-Loop for Transcriptional and Metabolic Modulation, Independent of Mitochondrial Fusion

Optic Atrophy 1 (OPA1) has well-established roles in both mitochondrial fusion and apoptotic crista remodeling and is required for the maintenance and distribution of mitochondrial DNA (mtDNA), which are essential for energy metabolism. However, the relationship between OPA1 and mitochondrial metabo...

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Detalles Bibliográficos
Autores principales:	Yang, Liang, Tang, Haite, Lin, Xiaobing, Wu, Yi, Zeng, Sheng, Pan, Yongzhang, Li, Yukun, Xiang, Ge, Lin, Yi-Fang, Zhuang, Shi-Mei, Song, Zhiyin, Jiang, Yiguo, Liu, Xingguo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Cell and Developmental Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7179665/ https://www.ncbi.nlm.nih.gov/pubmed/32373606 http://dx.doi.org/10.3389/fcell.2020.00180

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