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A New Series of Carlactonoic Acid Based Strigolactone Analogs for Fundamental and Applied Research

Strigolactones (SLs) are a group of carotenoid derived plant hormones that play a key role in establishing plant architecture and adapting it to environmental changes, and are involved in plants response to biotic and abiotic stress. SLs are also released into the soil to serve as a chemical signal...

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Autores principales: Jamil, Muhammad, Kountche, Boubacar A., Wang, Jian You, Haider, Imran, Jia, Kun-Peng, Takahashi, Ikuo, Ota, Tsuyoshi, Asami, Tadao, Al-Babili, Salim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7179673/
https://www.ncbi.nlm.nih.gov/pubmed/32373143
http://dx.doi.org/10.3389/fpls.2020.00434
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author Jamil, Muhammad
Kountche, Boubacar A.
Wang, Jian You
Haider, Imran
Jia, Kun-Peng
Takahashi, Ikuo
Ota, Tsuyoshi
Asami, Tadao
Al-Babili, Salim
author_facet Jamil, Muhammad
Kountche, Boubacar A.
Wang, Jian You
Haider, Imran
Jia, Kun-Peng
Takahashi, Ikuo
Ota, Tsuyoshi
Asami, Tadao
Al-Babili, Salim
author_sort Jamil, Muhammad
collection PubMed
description Strigolactones (SLs) are a group of carotenoid derived plant hormones that play a key role in establishing plant architecture and adapting it to environmental changes, and are involved in plants response to biotic and abiotic stress. SLs are also released into the soil to serve as a chemical signal attracting beneficial mycorrhizal fungi. However, this signal also induces seed germination in root parasitic weeds that represent a major global threat for agriculture. This wide spectrum of biological functions has made SL research one of the most important current topics in fundamental and applied plant science. The availability of SLs is crucial for investigating SL biology as well as for agricultural application. However, natural SLs are produced in very low amounts, and their organic synthesis is quite difficult, which creates a need for efficient and easy-to-synthesize analogs and mimics. Recently, we have generated a set of SL analogs, Methyl Phenlactonoates (MPs), which resemble the non-canonical SL carlactonoic acid. In this paper, we describe the development and characterization of a new series of easy-to-synthesize MPs. The new analogs were assessed with respect to regulation of shoot branching, impact on leaf senescence, and induction of seed germination in different root parasitic plants species. Some of the new analogs showed higher efficiency in inhibiting shoot branching as well as in triggering parasitic seed germination, compared to the commonly used GR24. MP16 was the most outstanding analog showing high activity in different SL biological functions. In summary, our new analogs series contains very promising candidates for different applications, which include the usage in studies for understanding different aspects of SL biology as well as large scale field application for combating root parasitic weeds, such as Striga hermonthica that devastates cereal yields in sub-Saharan Africa.
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spelling pubmed-71796732020-05-05 A New Series of Carlactonoic Acid Based Strigolactone Analogs for Fundamental and Applied Research Jamil, Muhammad Kountche, Boubacar A. Wang, Jian You Haider, Imran Jia, Kun-Peng Takahashi, Ikuo Ota, Tsuyoshi Asami, Tadao Al-Babili, Salim Front Plant Sci Plant Science Strigolactones (SLs) are a group of carotenoid derived plant hormones that play a key role in establishing plant architecture and adapting it to environmental changes, and are involved in plants response to biotic and abiotic stress. SLs are also released into the soil to serve as a chemical signal attracting beneficial mycorrhizal fungi. However, this signal also induces seed germination in root parasitic weeds that represent a major global threat for agriculture. This wide spectrum of biological functions has made SL research one of the most important current topics in fundamental and applied plant science. The availability of SLs is crucial for investigating SL biology as well as for agricultural application. However, natural SLs are produced in very low amounts, and their organic synthesis is quite difficult, which creates a need for efficient and easy-to-synthesize analogs and mimics. Recently, we have generated a set of SL analogs, Methyl Phenlactonoates (MPs), which resemble the non-canonical SL carlactonoic acid. In this paper, we describe the development and characterization of a new series of easy-to-synthesize MPs. The new analogs were assessed with respect to regulation of shoot branching, impact on leaf senescence, and induction of seed germination in different root parasitic plants species. Some of the new analogs showed higher efficiency in inhibiting shoot branching as well as in triggering parasitic seed germination, compared to the commonly used GR24. MP16 was the most outstanding analog showing high activity in different SL biological functions. In summary, our new analogs series contains very promising candidates for different applications, which include the usage in studies for understanding different aspects of SL biology as well as large scale field application for combating root parasitic weeds, such as Striga hermonthica that devastates cereal yields in sub-Saharan Africa. Frontiers Media S.A. 2020-04-15 /pmc/articles/PMC7179673/ /pubmed/32373143 http://dx.doi.org/10.3389/fpls.2020.00434 Text en Copyright © 2020 Jamil, Kountche, Wang, Haider, Jia, Takahashi, Ota, Asami and Al-Babili. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Plant Science
Jamil, Muhammad
Kountche, Boubacar A.
Wang, Jian You
Haider, Imran
Jia, Kun-Peng
Takahashi, Ikuo
Ota, Tsuyoshi
Asami, Tadao
Al-Babili, Salim
A New Series of Carlactonoic Acid Based Strigolactone Analogs for Fundamental and Applied Research
title A New Series of Carlactonoic Acid Based Strigolactone Analogs for Fundamental and Applied Research
title_full A New Series of Carlactonoic Acid Based Strigolactone Analogs for Fundamental and Applied Research
title_fullStr A New Series of Carlactonoic Acid Based Strigolactone Analogs for Fundamental and Applied Research
title_full_unstemmed A New Series of Carlactonoic Acid Based Strigolactone Analogs for Fundamental and Applied Research
title_short A New Series of Carlactonoic Acid Based Strigolactone Analogs for Fundamental and Applied Research
title_sort new series of carlactonoic acid based strigolactone analogs for fundamental and applied research
topic Plant Science
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7179673/
https://www.ncbi.nlm.nih.gov/pubmed/32373143
http://dx.doi.org/10.3389/fpls.2020.00434
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