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Iminosugars With Endoplasmic Reticulum α-Glucosidase Inhibitor Activity Inhibit ZIKV Replication and Reverse Cytopathogenicity in vitro

Zika virus (ZIKV), a vector-borne virus of the family Flaviviridae, continues to spread and remains a significant global public health threat. Currently, there are no approved vaccines or antivirals against ZIKV. We investigated the anti-ZIKV ability of three iminosugars with endoplasmic reticulum α...

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Detalles Bibliográficos
Autores principales: Bhushan, Gitanjali, Lim, Levina, Bird, Ian, Chothe, Shubhada K., Nissly, Ruth H., Kuchipudi, Suresh V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7179685/
https://www.ncbi.nlm.nih.gov/pubmed/32373079
http://dx.doi.org/10.3389/fmicb.2020.00531