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Study of SARS-CoV-2 in semen and urine samples of a volunteer with positive naso-pharyngeal swab

INTRODUCTION: The recent appearance of SARS-CoV-2 in Wuhan in 2019 has started a pandemic which has involved over a million people worldwide. A matter of debate is the possible viral detection in different body fluids than respiratory droplets. Thus, we evaluated the possible presence of SARS-CoV-2...

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Autores principales: Paoli, D., Pallotti, F., Colangelo, S., Basilico, F., Mazzuti, L., Turriziani, O., Antonelli, G., Lenzi, A., Lombardo, F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7179792/
https://www.ncbi.nlm.nih.gov/pubmed/32329026
http://dx.doi.org/10.1007/s40618-020-01261-1
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author Paoli, D.
Pallotti, F.
Colangelo, S.
Basilico, F.
Mazzuti, L.
Turriziani, O.
Antonelli, G.
Lenzi, A.
Lombardo, F.
author_facet Paoli, D.
Pallotti, F.
Colangelo, S.
Basilico, F.
Mazzuti, L.
Turriziani, O.
Antonelli, G.
Lenzi, A.
Lombardo, F.
author_sort Paoli, D.
collection PubMed
description INTRODUCTION: The recent appearance of SARS-CoV-2 in Wuhan in 2019 has started a pandemic which has involved over a million people worldwide. A matter of debate is the possible viral detection in different body fluids than respiratory droplets. Thus, we evaluated the possible presence of SARS-CoV-2 in semen and urine samples of a volunteer with confirmed COVID-19. MATERIALS AND METHODS: A 31-year-old man with fever, myalgia, anosmia, and ageusia was tested and found positive for SARS-CoV-2 through a pharyngeal swab. Eight days after he provided semen and urine samples in which viral RNA presence was measured using a Real time RT PCR system (RealStar SARS-CoV-2 RT-PCR, Altona Diagnostics) targeting E and S viral genes. RESULTS AND DISCUSSION: Semen and urine samples search for SARS-CoV-2 RNA was negative. Although this should be interpreted cautiously, it may be possible that either the viral clearance kinetics in these matrices matches the progressive clinical recovery of the patient or that the virus was never present in these fluids at the time of the laboratory diagnosis.
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spelling pubmed-71797922020-04-24 Study of SARS-CoV-2 in semen and urine samples of a volunteer with positive naso-pharyngeal swab Paoli, D. Pallotti, F. Colangelo, S. Basilico, F. Mazzuti, L. Turriziani, O. Antonelli, G. Lenzi, A. Lombardo, F. J Endocrinol Invest Rapid Communication INTRODUCTION: The recent appearance of SARS-CoV-2 in Wuhan in 2019 has started a pandemic which has involved over a million people worldwide. A matter of debate is the possible viral detection in different body fluids than respiratory droplets. Thus, we evaluated the possible presence of SARS-CoV-2 in semen and urine samples of a volunteer with confirmed COVID-19. MATERIALS AND METHODS: A 31-year-old man with fever, myalgia, anosmia, and ageusia was tested and found positive for SARS-CoV-2 through a pharyngeal swab. Eight days after he provided semen and urine samples in which viral RNA presence was measured using a Real time RT PCR system (RealStar SARS-CoV-2 RT-PCR, Altona Diagnostics) targeting E and S viral genes. RESULTS AND DISCUSSION: Semen and urine samples search for SARS-CoV-2 RNA was negative. Although this should be interpreted cautiously, it may be possible that either the viral clearance kinetics in these matrices matches the progressive clinical recovery of the patient or that the virus was never present in these fluids at the time of the laboratory diagnosis. Springer International Publishing 2020-04-23 2020 /pmc/articles/PMC7179792/ /pubmed/32329026 http://dx.doi.org/10.1007/s40618-020-01261-1 Text en © Italian Society of Endocrinology (SIE) 2020 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Rapid Communication
Paoli, D.
Pallotti, F.
Colangelo, S.
Basilico, F.
Mazzuti, L.
Turriziani, O.
Antonelli, G.
Lenzi, A.
Lombardo, F.
Study of SARS-CoV-2 in semen and urine samples of a volunteer with positive naso-pharyngeal swab
title Study of SARS-CoV-2 in semen and urine samples of a volunteer with positive naso-pharyngeal swab
title_full Study of SARS-CoV-2 in semen and urine samples of a volunteer with positive naso-pharyngeal swab
title_fullStr Study of SARS-CoV-2 in semen and urine samples of a volunteer with positive naso-pharyngeal swab
title_full_unstemmed Study of SARS-CoV-2 in semen and urine samples of a volunteer with positive naso-pharyngeal swab
title_short Study of SARS-CoV-2 in semen and urine samples of a volunteer with positive naso-pharyngeal swab
title_sort study of sars-cov-2 in semen and urine samples of a volunteer with positive naso-pharyngeal swab
topic Rapid Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7179792/
https://www.ncbi.nlm.nih.gov/pubmed/32329026
http://dx.doi.org/10.1007/s40618-020-01261-1
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