Ribosome binding protein GCN1 regulates the cell cycle and cell proliferation and is essential for the embryonic development of mice

Amino acids exert many biological functions, serving as allosteric regulators and neurotransmitters, as constituents in proteins and as nutrients. GCN2-mediated phosphorylation of eukaryotic initiation factor 2 alpha (elF2α) restores homeostasis in response to amino acid starvation (AAS) through the...

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Detalles Bibliográficos
Autores principales: Yamazaki, Hiromi, Kasai, Shuya, Mimura, Junsei, Ye, Peng, Inose-Maruyama, Atsushi, Tanji, Kunikazu, Wakabayashi, Koichi, Mizuno, Seiya, Sugiyama, Fumihiro, Takahashi, Satoru, Sato, Tsubasa, Ozaki, Taku, Cavener, Douglas R., Yamamoto, Masayuki, Itoh, Ken
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7179835/
https://www.ncbi.nlm.nih.gov/pubmed/32324833
http://dx.doi.org/10.1371/journal.pgen.1008693

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