Normal myeloid progenitor cell subset-associated gene signatures for acute myeloid leukaemia subtyping with prognostic impact

Acute myeloid leukaemia (AML) is characterised by phenotypic heterogeneity, which we hypothesise is a consequence of deregulated differentiation with transcriptional reminiscence of the normal compartment or cell-of-origin. Here, we propose a classification system based on normal myeloid progenitor...

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Detalles Bibliográficos
Autores principales: Schönherz, Anna A., Bødker, Julie Støve, Schmitz, Alexander, Brøndum, Rasmus Froberg, Jakobsen, Lasse Hjort, Roug, Anne Stidsholt, Severinsen, Marianne T., El-Galaly, Tarec C., Jensen, Paw, Johnsen, Hans Erik, Bøgsted, Martin, Dybkær, Karen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7179860/
https://www.ncbi.nlm.nih.gov/pubmed/32324791
http://dx.doi.org/10.1371/journal.pone.0229593

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