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Model‐Informed Drug Development for Everolimus Dosing Selection in Pediatric Infant Patients
Everolimus is currently approved in Europe as an adjunctive therapy for patients aged ≥ 2 years with tuberous sclerosis complex (TSC)–associated treatment‐refractory partial‐onset seizures, based on the EXIST‐3 study (NCT01713946) results. As TSC‐associated seizures can also affect children aged bet...
Autores principales: | Combes, Francois Pierre, Einolf, Heidi J., Coello, Neva, Heimbach, Tycho, He, Handan, Grosch, Kai |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7180003/ https://www.ncbi.nlm.nih.gov/pubmed/32150661 http://dx.doi.org/10.1002/psp4.12502 |
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