Cargando…

Same structure, different mechanisms?

Two interpretations of similar structures for the same molecular machine illustrate the limits of inferring biochemical mechanism from protein structure.

Detalles Bibliográficos
Autores principales: Tsai, Francis TF, Hill, Christopher P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7180051/
https://www.ncbi.nlm.nih.gov/pubmed/32321627
http://dx.doi.org/10.7554/eLife.56501
_version_ 1783525755503771648
author Tsai, Francis TF
Hill, Christopher P
author_facet Tsai, Francis TF
Hill, Christopher P
author_sort Tsai, Francis TF
collection PubMed
description Two interpretations of similar structures for the same molecular machine illustrate the limits of inferring biochemical mechanism from protein structure.
format Online
Article
Text
id pubmed-7180051
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher eLife Sciences Publications, Ltd
record_format MEDLINE/PubMed
spelling pubmed-71800512020-04-27 Same structure, different mechanisms? Tsai, Francis TF Hill, Christopher P eLife Structural Biology and Molecular Biophysics Two interpretations of similar structures for the same molecular machine illustrate the limits of inferring biochemical mechanism from protein structure. eLife Sciences Publications, Ltd 2020-04-23 /pmc/articles/PMC7180051/ /pubmed/32321627 http://dx.doi.org/10.7554/eLife.56501 Text en © 2020, Tsai and Hill http://creativecommons.org/licenses/by/4.0/ http://creativecommons.org/licenses/by/4.0/This article is distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use and redistribution provided that the original author and source are credited.
spellingShingle Structural Biology and Molecular Biophysics
Tsai, Francis TF
Hill, Christopher P
Same structure, different mechanisms?
title Same structure, different mechanisms?
title_full Same structure, different mechanisms?
title_fullStr Same structure, different mechanisms?
title_full_unstemmed Same structure, different mechanisms?
title_short Same structure, different mechanisms?
title_sort same structure, different mechanisms?
topic Structural Biology and Molecular Biophysics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7180051/
https://www.ncbi.nlm.nih.gov/pubmed/32321627
http://dx.doi.org/10.7554/eLife.56501
work_keys_str_mv AT tsaifrancistf samestructuredifferentmechanisms
AT hillchristopherp samestructuredifferentmechanisms