Aberrant Expression of High Mobility Group Box Protein 1 in the Idiopathic Inflammatory Myopathies

INTRODUCTION: High Mobility Group Box Protein 1 (HMGB1) is a DNA-binding protein that exerts inflammatory or pro-repair effects upon translocation from the nucleus. We postulate aberrant HMGB1 expression in immune-mediated necrotising myopathy (IMNM). METHODS: Herein, we compare HMGB1 expression (se...

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Detalles Bibliográficos
Autores principales: Day, Jessica, Otto, Sophia, Cash, Kathy, Eldi, Preethi, Hissaria, Pravin, Proudman, Susanna, Limaye, Vidya, Hayball, John D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7180187/
https://www.ncbi.nlm.nih.gov/pubmed/32363191
http://dx.doi.org/10.3389/fcell.2020.00226

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7180187/
https://www.ncbi.nlm.nih.gov/pubmed/32363191
http://dx.doi.org/10.3389/fcell.2020.00226

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