Bazedoxifene Attenuates Abdominal Aortic Aneurysm Formation via Downregulation of Interleukin-6/Glycoprotein 130/Signal Transducer and Activator of Transcription 3 Signaling Pathway in Apolipoprotein E–Knockout Mice

Abdominal aortic aneurysm (AAA) is a chronic inflammatory disease characterized by aortic dilatation and predominantly affects an elderly population. Accumulating evidence suggests that Interleukin-6 (IL-6) and the signal transducer and activator of transcription 3 (STAT3) play an important role in...

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Detalles Bibliográficos
Autores principales: Yan, Dan, Ma, Haiyan, Shi, Wei, Luo, Pengcheng, Liu, Tianshu, Guo, Junyi, Zhai, Maocai, Tao, Jingwen, Huo, Shengqi, Li, Chenglong, Lin, Jiayuh, Li, Sheng, Lv, Jiagao, Zhang, Cuntai, Lin, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7180191/
https://www.ncbi.nlm.nih.gov/pubmed/32362823
http://dx.doi.org/10.3389/fphar.2020.00392

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