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Intracellular Trafficking Mechanisms of Synaptic Dysfunction in Alzheimer’s Disease

Alzheimer’s disease (AD) is the most common neurodegenerative disease characterized by progressive memory loss. Although AD neuropathological hallmarks are extracellular amyloid plaques and intracellular tau tangles, the best correlate of disease progression is synapse loss. What causes synapse loss...

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Detalles Bibliográficos
Autores principales: Perdigão, Catarina, Barata, Mariana A., Araújo, Margarida N., Mirfakhar, Farzaneh S., Castanheira, Jorge, Guimas Almeida, Cláudia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7180223/
https://www.ncbi.nlm.nih.gov/pubmed/32362813
http://dx.doi.org/10.3389/fncel.2020.00072