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Intracellular Trafficking Mechanisms of Synaptic Dysfunction in Alzheimer’s Disease
Alzheimer’s disease (AD) is the most common neurodegenerative disease characterized by progressive memory loss. Although AD neuropathological hallmarks are extracellular amyloid plaques and intracellular tau tangles, the best correlate of disease progression is synapse loss. What causes synapse loss...
Autores principales: | Perdigão, Catarina, Barata, Mariana A., Araújo, Margarida N., Mirfakhar, Farzaneh S., Castanheira, Jorge, Guimas Almeida, Cláudia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7180223/ https://www.ncbi.nlm.nih.gov/pubmed/32362813 http://dx.doi.org/10.3389/fncel.2020.00072 |
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