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Direct Determination of Pyrazinamide (PZA) Susceptibility by Sputum Microscopic Observation Drug Susceptibility (MODS) Culture at Neutral pH: the MODS-PZA Assay

Pyrazinamide (PZA) is considered the pivot drug in all tuberculosis treatment regimens due to its particular action on the persistent forms of Mycobacterium tuberculosis. However, no drug susceptibility test (DST) is considered sufficiently reliable for routine application. Although molecular tests...

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Detalles Bibliográficos
Autores principales: Alcántara, Roberto, Fuentes, Patricia, Marin, Lisette, Kirwan, Daniela E., Gilman, Robert H., Zimic, Mirko, Sheen, Patricia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7180241/
https://www.ncbi.nlm.nih.gov/pubmed/32132191
http://dx.doi.org/10.1128/JCM.01165-19