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Biallelic correction of sickle cell disease‐derived induced pluripotent stem cells (iPSCs) confirmed at the protein level through serum‐free iPS‐sac/erythroid differentiation

New technologies of induced pluripotent stem cells (iPSCs) and genome editing have emerged, allowing for the development of autologous transfusion therapies. We previously demonstrated definitive β‐globin production from human embryonic stem cell (hESC)‐derived erythroid cell generation via hemangio...

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Detalles Bibliográficos
Autores principales: Haro‐Mora, Juan J., Uchida, Naoya, Demirci, Selami, Wang, Qi, Zou, Jizhong, Tisdale, John F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7180291/
https://www.ncbi.nlm.nih.gov/pubmed/32034898
http://dx.doi.org/10.1002/sctm.19-0216

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