The Effects of Hesperidin on Neuronal Apoptosis and Cognitive Impairment in the Sevoflurane Anesthetized Rat are Mediated Through the PI3/Akt/PTEN and Nuclear Factor-κB (NF-κB) Signaling Pathways

BACKGROUND: Hesperidin (HPD) is a bioflavonoid found in citrus fruits. This study aimed to investigate the effects of HPD on cerebral morphology and cognitive behavior in sevoflurane anesthetized neonatal rats and the molecular mechanisms involved. MATERIAL/METHODS: Sixty neonatal Sprague–Dawley rat...

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Detalles Bibliográficos
Autores principales: Huang, Haijin, Hu, Cuicui, Xu, Lin, Zhu, Xiaoping, Zhao, Lili, Min, Jia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2020
Materias:
Animal Study
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7180331/
https://www.ncbi.nlm.nih.gov/pubmed/32296010
http://dx.doi.org/10.12659/MSM.920522

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7180331/
https://www.ncbi.nlm.nih.gov/pubmed/32296010
http://dx.doi.org/10.12659/MSM.920522

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