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The Effects of Hesperidin on Neuronal Apoptosis and Cognitive Impairment in the Sevoflurane Anesthetized Rat are Mediated Through the PI3/Akt/PTEN and Nuclear Factor-κB (NF-κB) Signaling Pathways
BACKGROUND: Hesperidin (HPD) is a bioflavonoid found in citrus fruits. This study aimed to investigate the effects of HPD on cerebral morphology and cognitive behavior in sevoflurane anesthetized neonatal rats and the molecular mechanisms involved. MATERIAL/METHODS: Sixty neonatal Sprague–Dawley rat...
Autores principales: | Huang, Haijin, Hu, Cuicui, Xu, Lin, Zhu, Xiaoping, Zhao, Lili, Min, Jia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
International Scientific Literature, Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7180331/ https://www.ncbi.nlm.nih.gov/pubmed/32296010 http://dx.doi.org/10.12659/MSM.920522 |
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