Cargando…

Glutamine Analogues Impair Cell Proliferation, the Intracellular Cycle and Metacyclogenesis in Trypanosoma cruzi

Trypanosoma cruzi is the aetiologic agent of Chagas disease, which affects people in the Americas and worldwide. The parasite has a complex life cycle that alternates among mammalian hosts and insect vectors. During its life cycle, T. cruzi passes through different environments and faces nutrient sh...

Descripción completa

Detalles Bibliográficos
Autores principales:	Souza, Rodolpho Ornitz Oliveira, Crispim, Marcell, Silber, Ariel Mariano, Damasceno, Flávia Silva
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7180609/ https://www.ncbi.nlm.nih.gov/pubmed/32252252 http://dx.doi.org/10.3390/molecules25071628

Ejemplares similares

Fatty acid oxidation participates in resistance to nutrient-depleted environments in the insect stages of Trypanosoma cruzi
por: Souza, Rodolpho Ornitz Oliveira, et al.
Publicado: (2021)

The glutamine synthetase of Trypanosoma cruzi is required for its resistance to ammonium accumulation and evasion of the parasitophorous vacuole during host-cell infection
por: Crispim, Marcell, et al.
Publicado: (2018)

Memantine, an Antagonist of the NMDA Glutamate Receptor, Affects Cell Proliferation, Differentiation and the Intracellular Cycle and Induces Apoptosis in Trypanosoma cruzi
por: Damasceno, Flávia Silva, et al.
Publicado: (2014)

The regulation of autophagy differentially affects Trypanosoma cruzi metacyclogenesis
por: Vanrell, María Cristina, et al.
Publicado: (2017)

Transcriptional remodeling during metacyclogenesis in Trypanosoma cruzi I
por: Cruz-Saavedra, Lissa, et al.
Publicado: (2020)

Uptake of l-Alanine and Its Distinct Roles in the Bioenergetics of Trypanosoma cruzi
por: Girard, Richard M. B. M., et al.
Publicado: (2018)

Analysis of Proteasomal Proteolysis during the In Vitro Metacyclogenesis of Trypanosoma cruzi
por: Cardoso, Josiane, et al.
Publicado: (2011)

Revisiting the Trypanosoma cruzi metacyclogenesis: morphological and ultrastructural analyses during cell differentiation
por: Gonçalves, Camila Silva, et al.
Publicado: (2018)

Correction for Girard et al., “Uptake of l-Alanine and Its Distinct Roles in the Bioenergetics of Trypanosoma cruzi”
por: Girard, Richard M. B. M., et al.
Publicado: (2018)

The effect of temperature increase on the development of Rhodnius prolixus and the course of Trypanosoma cruzi metacyclogenesis
por: Tamayo, Laura D., et al.
Publicado: (2018)

Quantitative proteome and phosphoproteome analyses highlight the adherent population during Trypanosoma cruzi metacyclogenesis
por: Amorim, Juliana C., et al.
Publicado: (2017)

Expression and cellular trafficking of GP82 and GP90 glycoproteins during Trypanosoma cruzi metacyclogenesis
por: Bayer-Santos, Ethel, et al.
Publicado: (2013)

Metacyclogenesis defects and gene expression hallmarks of histone deacetylase 4-deficient Trypanosoma cruzi cells
por: Picchi-Constante, Gisele Fernanda Assine, et al.
Publicado: (2021)

An Iron Transporter Is Involved in Iron Homeostasis, Energy Metabolism, Oxidative Stress, and Metacyclogenesis in Trypanosoma cruzi
por: Dick, Claudia F., et al.
Publicado: (2022)

A Trypanosoma cruzi zinc finger protein that is implicated in the control of epimastigote-specific gene expression and metacyclogenesis
por: Tavares, Thais S., et al.
Publicado: (2021)

The effect of memantine, an antagonist of the NMDA glutamate receptor, in in vitro and in vivo infections by Trypanosoma cruzi
por: Santos Souza, Higo Fernando, et al.
Publicado: (2019)

MDL28170, a Calpain Inhibitor, Affects Trypanosoma cruzi Metacyclogenesis, Ultrastructure and Attachment to Rhodnius prolixus Midgut
por: Ennes-Vidal, Vítor, et al.
Publicado: (2011)

Actions of a Proline Analogue, L-Thiazolidine-4-Carboxylic Acid (T4C), on Trypanosoma cruzi
por: Magdaleno, Anahí, et al.
Publicado: (2009)

The Influence of Environmental Cues on the Development of Trypanosoma cruzi in Triatominae Vector
por: Melo, Raíssa de Fátima Pimentel, et al.
Publicado: (2020)

Genome-scale metabolic models highlight stage-specific differences in essential metabolic pathways in Trypanosoma cruzi
por: Shiratsubaki, Isabel S., et al.
Publicado: (2020)

Stress-Induced Proliferation and Cell Cycle Plasticity of Intracellular Trypanosoma cruzi Amastigotes
por: Dumoulin, Peter C., et al.
Publicado: (2018)

Glutamine metabolism modulates azole susceptibility in Trypanosoma cruzi amastigotes
por: Dumoulin, Peter C, et al.
Publicado: (2020)

Proline Dehydrogenase Regulates Redox State and Respiratory Metabolism in Trypanosoma cruzi
por: Paes, Lisvane Silva, et al.
Publicado: (2013)

Investigation of pyrimidine nucleoside analogues as chemical probes to assess compound effects on the proliferation of Trypanosoma cruzi intracellular parasites
por: Sykes, Melissa Louise, et al.
Publicado: (2020)

An aromatic imidazoline derived from chloroquinoline triggers cell cycle arrest and inhibits with high selectivity the Trypanosoma cruzi mammalian host-cells infection
por: Cuevas-Hernández, Roberto I., et al.
Publicado: (2021)

Glyceraldehyde 3-Phosphate Dehydrogenase-Telomere Association Correlates with Redox Status in Trypanosoma cruzi
por: Pariona-Llanos, Ricardo, et al.
Publicado: (2015)

Activity of Estafietin and Analogues on Trypanosoma cruzi and Leishmania braziliensis
por: Sülsen, Valeria P., et al.
Publicado: (2019)

Leishmania Metacyclogenesis Is Promoted in the Absence of Purines
por: Serafim, Tiago Donatelli, et al.
Publicado: (2012)

The Trypanosoma cruzi Protein TcHTE Is Critical for Heme Uptake
por: Merli, Marcelo L., et al.
Publicado: (2016)

The Trypanosoma cruzi TcrNT2 Nucleoside Transporter Is a Conduit for the Uptake of 5-F-2′-Deoxyuridine and Tubercidin Analogues
por: Aldfer, Mustafa M., et al.
Publicado: (2022)

The Involvement of Glutamate Metabolism in the Resistance to Thermal, Nutritional, and Oxidative Stress in Trypanosoma cruzi
por: Magdaleno, Anahí, et al.
Publicado: (2011)

Combined Treatment of Heterocyclic Analogues and Benznidazole upon Trypanosoma cruzi In Vivo
por: Batista, Denise da Gama Jaén, et al.
Publicado: (2011)

Trypanosoma cruzi: mechanism of entry and intracellular fate in mammalian cells
Publicado: (1976)

The Intracellular Amastigote of Trypanosoma cruzi Maintains an Actively Beating Flagellum
por: Won, Madalyn M., et al.
Publicado: (2023)

Nucleosome landscape reflects phenotypic differences in Trypanosoma cruzi life forms
por: Lima, Alex R. J., et al.
Publicado: (2021)

In vitro and in silico analysis of imatinib analogues as anti-Trypanosoma cruzi drug candidates
por: Nesic de Freitas, Luca S. F., et al.
Publicado: (2023)

Transcriptome Remodeling in Trypanosoma cruzi and Human Cells during Intracellular Infection
por: Li, Yuan, et al.
Publicado: (2016)

Nanocarrier-enhanced intracellular delivery of benznidazole for treatment of Trypanosoma cruzi infection
por: Li, Xiaomo, et al.
Publicado: (2021)

Impact of Laboratory-Adapted Intracellular Trypanosoma cruzi Strains on the Activity Profiles of Compounds with Anti-T. cruzi Activity
por: Sykes, Melissa L., et al.
Publicado: (2023)

Immune Evasion Strategies of Trypanosoma cruzi
por: Flávia Nardy, Ana, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_orfm24jeldk90vjsdusgtdqbn2