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Encapsulation for Cancer Therapy
The current rapid advancement of numerous nanotechnology tools is being employed in treatment of many terminal diseases such as cancer. Nanocapsules (NCs) containing an anti-cancer drug offer a very promising alternative to conventional treatments, mostly due to their targeted delivery and precise a...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7180689/ https://www.ncbi.nlm.nih.gov/pubmed/32244513 http://dx.doi.org/10.3390/molecules25071605 |
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author | Montané, Xavier Bajek, Anna Roszkowski, Krzysztof Montornés, Josep M. Giamberini, Marta Roszkowski, Szymon Kowalczyk, Oliwia Garcia-Valls, Ricard Tylkowski, Bartosz |
author_facet | Montané, Xavier Bajek, Anna Roszkowski, Krzysztof Montornés, Josep M. Giamberini, Marta Roszkowski, Szymon Kowalczyk, Oliwia Garcia-Valls, Ricard Tylkowski, Bartosz |
author_sort | Montané, Xavier |
collection | PubMed |
description | The current rapid advancement of numerous nanotechnology tools is being employed in treatment of many terminal diseases such as cancer. Nanocapsules (NCs) containing an anti-cancer drug offer a very promising alternative to conventional treatments, mostly due to their targeted delivery and precise action, and thereby they can be used in distinct applications: as biosensors or in medical imaging, allowing for cancer detection as well as agents/carriers in targeted drug delivery. The possibility of using different systems—inorganic nanoparticles, dendrimers, proteins, polymeric micelles, liposomes, carbon nanotubes (CNTs), quantum dots (QDs), biopolymeric nanoparticles and their combinations—offers multiple benefits to early cancer detection as well as controlled drug delivery to specific locations. This review focused on the key and recent progress in the encapsulation of anticancer drugs that include methods of preparation, drug loading and drug release mechanism on the presented nanosystems. Furthermore, the future directions in applications of various nanoparticles are highlighted. |
format | Online Article Text |
id | pubmed-7180689 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-71806892020-05-01 Encapsulation for Cancer Therapy Montané, Xavier Bajek, Anna Roszkowski, Krzysztof Montornés, Josep M. Giamberini, Marta Roszkowski, Szymon Kowalczyk, Oliwia Garcia-Valls, Ricard Tylkowski, Bartosz Molecules Review The current rapid advancement of numerous nanotechnology tools is being employed in treatment of many terminal diseases such as cancer. Nanocapsules (NCs) containing an anti-cancer drug offer a very promising alternative to conventional treatments, mostly due to their targeted delivery and precise action, and thereby they can be used in distinct applications: as biosensors or in medical imaging, allowing for cancer detection as well as agents/carriers in targeted drug delivery. The possibility of using different systems—inorganic nanoparticles, dendrimers, proteins, polymeric micelles, liposomes, carbon nanotubes (CNTs), quantum dots (QDs), biopolymeric nanoparticles and their combinations—offers multiple benefits to early cancer detection as well as controlled drug delivery to specific locations. This review focused on the key and recent progress in the encapsulation of anticancer drugs that include methods of preparation, drug loading and drug release mechanism on the presented nanosystems. Furthermore, the future directions in applications of various nanoparticles are highlighted. MDPI 2020-03-31 /pmc/articles/PMC7180689/ /pubmed/32244513 http://dx.doi.org/10.3390/molecules25071605 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Montané, Xavier Bajek, Anna Roszkowski, Krzysztof Montornés, Josep M. Giamberini, Marta Roszkowski, Szymon Kowalczyk, Oliwia Garcia-Valls, Ricard Tylkowski, Bartosz Encapsulation for Cancer Therapy |
title | Encapsulation for Cancer Therapy |
title_full | Encapsulation for Cancer Therapy |
title_fullStr | Encapsulation for Cancer Therapy |
title_full_unstemmed | Encapsulation for Cancer Therapy |
title_short | Encapsulation for Cancer Therapy |
title_sort | encapsulation for cancer therapy |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7180689/ https://www.ncbi.nlm.nih.gov/pubmed/32244513 http://dx.doi.org/10.3390/molecules25071605 |
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