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The Role of Brassica Bioactives on Human Health: Are We Studying It the Right Way?

Brassica vegetables and their components, the glucosinolates, have been suggested as good candidates as dietary coadjutants to improve health in non-communicable diseases (NCDs). Different preclinical and clinical studies have been performed in the last decade; however, some concerns have been posed...

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Detalles Bibliográficos
Autores principales: Quirante-Moya, Sarai, García-Ibañez, Paula, Quirante-Moya, Francisco, Villaño, Débora, Moreno, Diego A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7180841/
https://www.ncbi.nlm.nih.gov/pubmed/32235638
http://dx.doi.org/10.3390/molecules25071591
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author Quirante-Moya, Sarai
García-Ibañez, Paula
Quirante-Moya, Francisco
Villaño, Débora
Moreno, Diego A.
author_facet Quirante-Moya, Sarai
García-Ibañez, Paula
Quirante-Moya, Francisco
Villaño, Débora
Moreno, Diego A.
author_sort Quirante-Moya, Sarai
collection PubMed
description Brassica vegetables and their components, the glucosinolates, have been suggested as good candidates as dietary coadjutants to improve health in non-communicable diseases (NCDs). Different preclinical and clinical studies have been performed in the last decade; however, some concerns have been posed on the lack of established and standardized protocols. The different concentration of bioactive compounds used, time of intervention or sample size, and the lack of blinding are some factors that may influence the studies’ outcomes. This review aims to analyze the critical points of the studies performed with Brassica-related biomolecules and propose some bases for future trials in order to avoid biases.
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spelling pubmed-71808412020-05-01 The Role of Brassica Bioactives on Human Health: Are We Studying It the Right Way? Quirante-Moya, Sarai García-Ibañez, Paula Quirante-Moya, Francisco Villaño, Débora Moreno, Diego A. Molecules Review Brassica vegetables and their components, the glucosinolates, have been suggested as good candidates as dietary coadjutants to improve health in non-communicable diseases (NCDs). Different preclinical and clinical studies have been performed in the last decade; however, some concerns have been posed on the lack of established and standardized protocols. The different concentration of bioactive compounds used, time of intervention or sample size, and the lack of blinding are some factors that may influence the studies’ outcomes. This review aims to analyze the critical points of the studies performed with Brassica-related biomolecules and propose some bases for future trials in order to avoid biases. MDPI 2020-03-30 /pmc/articles/PMC7180841/ /pubmed/32235638 http://dx.doi.org/10.3390/molecules25071591 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Quirante-Moya, Sarai
García-Ibañez, Paula
Quirante-Moya, Francisco
Villaño, Débora
Moreno, Diego A.
The Role of Brassica Bioactives on Human Health: Are We Studying It the Right Way?
title The Role of Brassica Bioactives on Human Health: Are We Studying It the Right Way?
title_full The Role of Brassica Bioactives on Human Health: Are We Studying It the Right Way?
title_fullStr The Role of Brassica Bioactives on Human Health: Are We Studying It the Right Way?
title_full_unstemmed The Role of Brassica Bioactives on Human Health: Are We Studying It the Right Way?
title_short The Role of Brassica Bioactives on Human Health: Are We Studying It the Right Way?
title_sort role of brassica bioactives on human health: are we studying it the right way?
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7180841/
https://www.ncbi.nlm.nih.gov/pubmed/32235638
http://dx.doi.org/10.3390/molecules25071591
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