Recent Advances in Synthesis of Benzothiazole Compounds Related to Green Chemistry

Benzothiazoles have played an important role in the field of biochemistry and medicinal chemistry due to their highly pharmaceutical and biological activity. The development of synthetic processes is undoubtedly one of the most significant problems facing researchers. In this review paper, we provid...

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Detalles Bibliográficos
Autores principales: Gao, Xiang, Liu, Jiao, Zuo, Xin, Feng, Xinyue, Gao, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7181030/
https://www.ncbi.nlm.nih.gov/pubmed/32260500
http://dx.doi.org/10.3390/molecules25071675
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author Gao, Xiang
Liu, Jiao
Zuo, Xin
Feng, Xinyue
Gao, Ying
author_facet Gao, Xiang
Liu, Jiao
Zuo, Xin
Feng, Xinyue
Gao, Ying
author_sort Gao, Xiang
collection PubMed
description Benzothiazoles have played an important role in the field of biochemistry and medicinal chemistry due to their highly pharmaceutical and biological activity. The development of synthetic processes is undoubtedly one of the most significant problems facing researchers. In this review paper, we provided recent advances in the synthesis of benzothiazole compounds related to green chemistry from condensation of 2-aminobenzenethiol with aldehydes/ketones/acids/acyl chlorides and the cyclization of thioamide or carbon dioxide (CO(2)) as raw materials, and the future development trend and prospect of the synthesis of benzothiazoles were anticipated.
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spelling pubmed-71810302020-04-30 Recent Advances in Synthesis of Benzothiazole Compounds Related to Green Chemistry Gao, Xiang Liu, Jiao Zuo, Xin Feng, Xinyue Gao, Ying Molecules Review Benzothiazoles have played an important role in the field of biochemistry and medicinal chemistry due to their highly pharmaceutical and biological activity. The development of synthetic processes is undoubtedly one of the most significant problems facing researchers. In this review paper, we provided recent advances in the synthesis of benzothiazole compounds related to green chemistry from condensation of 2-aminobenzenethiol with aldehydes/ketones/acids/acyl chlorides and the cyclization of thioamide or carbon dioxide (CO(2)) as raw materials, and the future development trend and prospect of the synthesis of benzothiazoles were anticipated. MDPI 2020-04-05 /pmc/articles/PMC7181030/ /pubmed/32260500 http://dx.doi.org/10.3390/molecules25071675 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Gao, Xiang
Liu, Jiao
Zuo, Xin
Feng, Xinyue
Gao, Ying
Recent Advances in Synthesis of Benzothiazole Compounds Related to Green Chemistry
title Recent Advances in Synthesis of Benzothiazole Compounds Related to Green Chemistry
title_full Recent Advances in Synthesis of Benzothiazole Compounds Related to Green Chemistry
title_fullStr Recent Advances in Synthesis of Benzothiazole Compounds Related to Green Chemistry
title_full_unstemmed Recent Advances in Synthesis of Benzothiazole Compounds Related to Green Chemistry
title_short Recent Advances in Synthesis of Benzothiazole Compounds Related to Green Chemistry
title_sort recent advances in synthesis of benzothiazole compounds related to green chemistry
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7181030/
https://www.ncbi.nlm.nih.gov/pubmed/32260500
http://dx.doi.org/10.3390/molecules25071675
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