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Probing the Protein-Protein Interaction between the ATRX(ADD) Domain and the Histone H3 Tail

While loss-of-function mutations in the ATRX gene have been implicated as a driving force for a variety of pediatric brain tumors, as well as pancreatic neuroendocrine tumors, the role of ATRX in gene regulation and oncogenic development is not well-characterized. The ADD domain of ATRX (ATRX(ADD))...

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Detalles Bibliográficos
Autores principales: Zaino, Angela M., Dash, Radha Charan, Hadden, M. Kyle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7181051/
https://www.ncbi.nlm.nih.gov/pubmed/32218364
http://dx.doi.org/10.3390/molecules25071500

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