Cargando…
Synthesis, Structure and In Vitro Anti-Trypanosomal Activity of Non-Toxic Arylpyrrole-Based Chalcone Derivatives
With an intention of identifying chalcone derivatives exhibiting anti-protozoal activity, a cohort of relatively unexplored arylpyrrole-based chalcone derivatives were synthesized in moderate to good yields. The resultant compounds were evaluated in vitro for their potential activity against a cultu...
Autores principales: | Zulu, Ayanda I., Oderinlo, Ogunyemi O., Kruger, Cuan, Isaacs, Michelle, Hoppe, Heinrich C., Smith, Vincent J., Veale, Clinton G. L., Khanye, Setshaba D. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7181280/ https://www.ncbi.nlm.nih.gov/pubmed/32260364 http://dx.doi.org/10.3390/molecules25071668 |
Ejemplares similares
-
Anti-Trypanosomal and Antimalarial Properties of Tetralone Derivatives and Structurally Related Benzocycloalkanones
por: Beteck, Richard M., et al.
Publicado: (2019) -
Discovery of Novel Thiazolidinedione-Derivatives with Multi-Modal Antidiabetic Activities In Vitro and In Silico
por: Arineitwe, Charles, et al.
Publicado: (2023) -
Screening of the Pathogen Box reveals new starting points for anti-trypanosomal drug discovery
por: Veale, Clinton G. L., et al.
Publicado: (2018) -
Coumarin-Annulated Ferrocenyl 1,3-Oxazine Derivatives Possessing In Vitro Antimalarial and Antitrypanosomal Potency
por: Mbaba, Mziyanda, et al.
Publicado: (2021) -
Atroposelective Synthesis of Axially Chiral N‐Arylpyrroles by Chiral‐at‐Rhodium Catalysis
por: Ye, Chen‐Xi, et al.
Publicado: (2020)