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T Follicular Regulatory Cell Suppression of T Follicular Helper Cell Function Is Context-Dependent in vitro

The production of antibody-secreting plasma cells and memory B cells requires the interaction of T follicular helper (Tfh) cells with B cells in the follicle and is modulated by T follicular regulatory (Tfr) cells. We compare the effects of Tfr cells in an in vitro model of bystander Tfh function in...

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Detalles Bibliográficos
Autores principales: Lopez-Ocasio, Maria, Buszko, Maja, Blain, Melissa, Wang, Ke, Shevach, Ethan M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7181357/
https://www.ncbi.nlm.nih.gov/pubmed/32362895
http://dx.doi.org/10.3389/fimmu.2020.00637