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IL-35 is critical in suppressing superantigenic Staphylococcus aureus-driven inflammatory Th17 responses in human nasopharynx-associated lymphoid tissue

The human nasopharynx is frequently exposed to microbial pathogens, including superantigen-producing Staphylococcus aureus (SAg-Sau), which activates potent pro-inflammatory T cell responses. However, cellular mechanisms that control SAg-Sau-driven T cell activation are poorly understood. Using huma...

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Detalles Bibliográficos
Autores principales: Xu, Rong, Shears, Rebecca K., Sharma, Ravi, Krishna, Madhan, Webb, Christopher, Ali, Richard, Wei, Xiaoqing, Kadioglu, Aras, Zhang, Qibo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7181393/
https://www.ncbi.nlm.nih.gov/pubmed/31896761
http://dx.doi.org/10.1038/s41385-019-0246-1