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Direct Binding and Regulation by Fur and HapR of the Intermediate Regulator and Virulence Factor Genes Within the ToxR Virulence Regulon in Vibrio cholerae

Cholera toxin (CT) and toxin coregulated pilus (TCP, TcpA is the major subunit) are two major virulence factors of Vibrio cholerae, both of which play critical roles in developing severe diarrhea in human. Expression of CT and TCP is under the tight control of the regulatory cascade known as the Tox...

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Detalles Bibliográficos
Autores principales: Gao, He, Zhang, Jingyun, Lou, Jing, Li, Jie, Qin, Qin, Shi, Qiannan, Zhang, Yiquan, Kan, Biao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7181404/
https://www.ncbi.nlm.nih.gov/pubmed/32362889
http://dx.doi.org/10.3389/fmicb.2020.00709

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