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Synaptotagmin 13 is neuroprotective across motor neuron diseases

In amyotrophic lateral sclerosis (ALS) and spinal muscular atrophy (SMA), spinal and lower brainstem motor neurons degenerate, but some motor neuron subtypes are spared, including oculomotor neurons (OMNs). The mechanisms responsible for this selective degeneration are largely unknown, but the molec...

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Detalles Bibliográficos
Autores principales: Nizzardo, M., Taiana, M., Rizzo, F., Aguila Benitez, J., Nijssen, J., Allodi, I., Melzi, V., Bresolin, N., Comi, G. P., Hedlund, E., Corti, S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7181443/
https://www.ncbi.nlm.nih.gov/pubmed/32065260
http://dx.doi.org/10.1007/s00401-020-02133-x

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