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Different associations of tumor PIK3CA mutations and clinical outcomes according to aspirin use among women with metastatic hormone receptor positive breast cancer

INTRODUCTION: The relationships among PIK3CA mutations, medication use and tumor progression remains poorly understood. Aspirin use post-diagnosis may modify components of the PI3K pathway, including AKT and mTOR, and has been associated with lower risk of breast cancer recurrence and mortality. We...

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Detalles Bibliográficos
Autores principales: McCarthy, Anne Marie, Kumar, Nitya Pradeep, He, Wei, Regan, Susan, Welch, Michaela, Moy, Beverly, Iafrate, A. John, Chan, Andrew T., Bardia, Aditya, Armstrong, Katrina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7181475/
https://www.ncbi.nlm.nih.gov/pubmed/32326897
http://dx.doi.org/10.1186/s12885-020-06810-8