Cargando…
Different associations of tumor PIK3CA mutations and clinical outcomes according to aspirin use among women with metastatic hormone receptor positive breast cancer
INTRODUCTION: The relationships among PIK3CA mutations, medication use and tumor progression remains poorly understood. Aspirin use post-diagnosis may modify components of the PI3K pathway, including AKT and mTOR, and has been associated with lower risk of breast cancer recurrence and mortality. We...
Autores principales: | McCarthy, Anne Marie, Kumar, Nitya Pradeep, He, Wei, Regan, Susan, Welch, Michaela, Moy, Beverly, Iafrate, A. John, Chan, Andrew T., Bardia, Aditya, Armstrong, Katrina |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7181475/ https://www.ncbi.nlm.nih.gov/pubmed/32326897 http://dx.doi.org/10.1186/s12885-020-06810-8 |
Ejemplares similares
-
Mutations in PIK3CA sensitize breast cancer cells to physiologic levels of aspirin
por: Turturro, Sanja B., et al.
Publicado: (2016) -
Aspirin sensitivity of PIK3CA-mutated Colorectal Cancer: potential mechanisms revisited
por: Hall, Daniella C. N., et al.
Publicado: (2022) -
Aspirin exerts high anti-cancer activity in PIK3CA-mutant colon cancer cells
por: Gu, Mancang, et al.
Publicado: (2017) -
Deactivation of Glutaminolysis Sensitizes PIK3CA-Mutated Colorectal Cancer Cells to Aspirin-Induced Growth Inhibition
por: Boku, Shogen, et al.
Publicado: (2020) -
Carcinogenesis of PIK3CA
por: German, Sidra, et al.
Publicado: (2013)