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Influence of Nodal signalling on pluripotency factor expression, tumour cell proliferation and cisplatin-sensitivity in testicular germ cell tumours
BACKGROUND: Testicular germ cell tumours (TGCTs) are characterised by an overall high cisplatin-sensitivity which has been linked to their continued expression of pluripotency factors. Recently, the Nodal signalling pathway has been implicated in the regulation of pluripotency factor expression in f...
Autores principales: | Harpelunde Poulsen, K., Nielsen, J. E., Grønkær Toft, B., Joensen, U. N., Rasmussen, L. J., Blomberg Jensen, M., Mitchell, R. T., Juul, A., Rajpert-De Meyts, E., Jørgensen, A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7181506/ https://www.ncbi.nlm.nih.gov/pubmed/32326899 http://dx.doi.org/10.1186/s12885-020-06820-6 |
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