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T cell infiltration in both human multiple system atrophy and a novel mouse model of the disease

Multiple system atrophy (MSA) is a progressive neurodegenerative disorder characterized by abnormal accumulation of alpha-synuclein (α-syn) in oligodendrocytes accompanied by inflammation, demyelination, and subsequent synapse and neuronal loss. Little is known about the mechanisms of neurodegenerat...

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Detalles Bibliográficos
Autores principales: Williams, Gregory P., Marmion, David J., Schonhoff, Aubrey M., Jurkuvenaite, Asta, Won, Woong-Jai, Standaert, David G., Kordower, Jeffrey H., Harms, Ashley S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7181566/
https://www.ncbi.nlm.nih.gov/pubmed/31993745
http://dx.doi.org/10.1007/s00401-020-02126-w

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