DKK3 attenuates JNK and AP-1 induced inflammation via Kremen-1 and DVL-1 in mice following intracerebral hemorrhage

BACKGROUND: Intracerebral hemorrhage (ICH) is the most devastating stroke subtype, with a poor prognosis and few proven treatments. Neuroinflammation is associated with ICH-induced brain injury and unfavorable outcomes. There is growing evidence that Dickkopf (DKK) 3 plays a key role in the adaptive...

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Autores principales: Xu, Yang, Nowrangi, Derek, Liang, Hui, Wang, Tian, Yu, Lingyan, Lu, Tai, Lu, Zhengyang, Zhang, John H., Luo, Benyan, Tang, Jiping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7181567/
https://www.ncbi.nlm.nih.gov/pubmed/32331523
http://dx.doi.org/10.1186/s12974-020-01794-5

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