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EV71 virus reduces Nrf2 activation to promote production of reactive oxygen species in infected cells

BACKGROUND: Emerging evidence closely links Enterovirus 71 (EV71) infection with the generation of reactive oxygen species (ROS). Excess ROS results in apoptosis and exacerbates inflammatory reactions. The Keap1–Nrf2 axis serves as an essential oxidant counteracting pathway. METHODS: The present stu...

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Detalles Bibliográficos
Autores principales:	Bai, Zhenzi, Zhao, Xiaonan, Li, Chenghua, Sheng, Chuanlun, Li, Hongyan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7181592/ https://www.ncbi.nlm.nih.gov/pubmed/32346399 http://dx.doi.org/10.1186/s13099-020-00361-w

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