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FOXL2 directs DNA double-strand break repair pathways by differentially interacting with Ku

The balance between major DNA double-strand break (DSB) repair pathways is influenced by binding of the Ku complex, a XRCC5/6 heterodimer, to DSB ends, initiating non-homologous end joining (NHEJ) but preventing additional DSB end resection and homologous recombination (HR). However, the key molecul...

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Detalles Bibliográficos
Autores principales: Jin, Hanyong, Lee, Boeun, Luo, Yongyang, Choi, Yuri, Choi, Eui-Hwan, Jin, Hong, Kim, Kee-Beom, Seo, Sang Beom, Kim, Yong-Hak, Lee, Hyung Ho, Kim, Keun Pil, Lee, Kangseok, Bae, Jeehyeon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7181608/
https://www.ncbi.nlm.nih.gov/pubmed/32332759
http://dx.doi.org/10.1038/s41467-020-15748-1