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Novel Variations in Native Ethiopian Goat breeds PRNP Gene and Their Potential Effect on Prion Protein Stability

Scrapie is a lethal neurodegenerative disease of sheep and goats caused by the misfolding of the prion protein. Variants such as M142, D145, S146, H154, Q211, and K222 were experimentally found to increase resistance or extend scrapie incubation period in goats. We aimed to identify polymorphisms in...

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Detalles Bibliográficos
Autores principales:	Teferedegn, Eden Yitna, Yaman, Yalçın, Ün, Cemal
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7181617/ https://www.ncbi.nlm.nih.gov/pubmed/32332800 http://dx.doi.org/10.1038/s41598-020-63874-z

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