SK channel-mediated metabolic escape to glycolysis inhibits ferroptosis and supports stress resistance in C. elegans

Metabolic flexibility is an essential characteristic of eukaryotic cells in order to adapt to physiological and environmental changes. Especially in mammalian cells, the metabolic switch from mitochondrial respiration to aerobic glycolysis provides flexibility to sustain cellular energy in pathophys...

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Detalles Bibliográficos
Autores principales: Krabbendam, Inge E., Honrath, Birgit, Dilberger, Benjamin, Iannetti, Eligio F., Branicky, Robyn S., Meyer, Tammo, Evers, Bernard, Dekker, Frank J., Koopman, Werner J. H., Beyrath, Julien, Bano, Daniele, Schmidt, Martina, Bakker, Barbara M., Hekimi, Siegfried, Culmsee, Carsten, Eckert, Gunter P., Dolga, Amalia M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7181639/
https://www.ncbi.nlm.nih.gov/pubmed/32327637
http://dx.doi.org/10.1038/s41419-020-2458-4

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