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E2F1 mediated DDX11 transcriptional activation promotes hepatocellular carcinoma progression through PI3K/AKT/mTOR pathway

The DEAD/DEAH box helicase 11 (DDX11) plays vital roles in regulating the initiation of DNA replication. However, its precise function and regulation in hepatocellular carcinoma (HCC) have never been reported yet. In the current study, we found that DDX11 was overexpressed in HCC tissues. High DDX11...

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Detalles Bibliográficos
Autores principales: Yu, Yan, Zhao, Dan, Li, Kongfei, Cai, Yubo, Xu, Penglin, Li, Rui, Li, Juan, Chen, Xiaolong, Chen, Ping, Cui, Guangying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7181644/
https://www.ncbi.nlm.nih.gov/pubmed/32332880
http://dx.doi.org/10.1038/s41419-020-2478-0