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E2F1 mediated DDX11 transcriptional activation promotes hepatocellular carcinoma progression through PI3K/AKT/mTOR pathway
The DEAD/DEAH box helicase 11 (DDX11) plays vital roles in regulating the initiation of DNA replication. However, its precise function and regulation in hepatocellular carcinoma (HCC) have never been reported yet. In the current study, we found that DDX11 was overexpressed in HCC tissues. High DDX11...
Autores principales: | Yu, Yan, Zhao, Dan, Li, Kongfei, Cai, Yubo, Xu, Penglin, Li, Rui, Li, Juan, Chen, Xiaolong, Chen, Ping, Cui, Guangying |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7181644/ https://www.ncbi.nlm.nih.gov/pubmed/32332880 http://dx.doi.org/10.1038/s41419-020-2478-0 |
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