LncRNA GOLGA2P10 is induced by PERK/ATF4/CHOP signaling and protects tumor cells from ER stress-induced apoptosis by regulating Bcl-2 family members

Elevated endoplasmic reticulum (ER) stress is frequently observed in cancers, whereas sustained ER stress may trigger apoptosis. How cancer cells escape from ER stress-induced apoptosis remain unclear. Here, we found that a pseudogene-derived lncRNA, Golgin A2 pseudogene 10 (GOLGA2P10), was frequent...

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Detalles Bibliográficos
Autores principales: Wu, Meng-Zhi, Fu, Tao, Chen, Jin-Xi, Lin, Ying-Ying, Yang, Jin-E, Zhuang, Shi-Mei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7181651/
https://www.ncbi.nlm.nih.gov/pubmed/32332695
http://dx.doi.org/10.1038/s41419-020-2469-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7181651/
https://www.ncbi.nlm.nih.gov/pubmed/32332695
http://dx.doi.org/10.1038/s41419-020-2469-1

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