Cargando…

Cardiac remodeling and arrhythmogenesis are ameliorated by administration of Cx43 mimetic peptide Gap27 in heart failure rats

Alterations in connexins and specifically in 43 isoform (Cx43) in the heart have been associated with a high incidence of arrhythmogenesis and sudden death in several cardiac diseases. We propose to determine salutary effect of Cx43 mimetic peptide Gap27 in the progression of heart failure. High-out...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lucero, Claudia M., Andrade, David C., Toledo, Camilo, Díaz, Hugo S., Pereyra, Katherin V., Diaz-Jara, Esteban, Schwarz, Karla G., Marcus, Noah J., Retamal, Mauricio A., Quintanilla, Rodrigo A., Del Rio, Rodrigo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7181683/ https://www.ncbi.nlm.nih.gov/pubmed/32327677 http://dx.doi.org/10.1038/s41598-020-63336-6

Ejemplares similares

Chemogenetic inhibition of NTS astrocytes normalizes cardiac autonomic control and ameliorate hypertension during chronic intermittent hypoxia
por: Pereyra, Katherin, et al.
Publicado: (2023)

Exercise intolerance in volume overload heart failure is associated with low carotid body mediated chemoreflex drive
por: Andrade, David C., et al.
Publicado: (2021)

Medullary astrocytes mediate irregular breathing patterns generation in chronic heart failure through purinergic P2X7 receptor signalling
por: Toledo, Camilo, et al.
Publicado: (2022)

Episodic stimulation of central chemoreceptor neurons elicits disordered breathing and autonomic dysfunction in volume overload heart failure
por: Díaz, Hugo S., et al.
Publicado: (2020)

Cognitive impairment in heart failure is associated with altered Wnt signaling in the hippocampus
por: Toledo, Camilo, et al.
Publicado: (2019)

Connexin 43 mimetic peptide Gap27 reveals potential differences in the role of Cx43 in wound repair between diabetic and non-diabetic cells
por: Pollok, Simone, et al.
Publicado: (2011)

The Connexin Mimetic Peptide Gap27 and Cx43-Knockdown Reveal Differential Roles for Connexin43 in Wound Closure Events in Skin Model Systems
por: Faniku, Chrysovalantou, et al.
Publicado: (2018)

GABAergic Regulation of Astroglial Gliotransmission through Cx43 Hemichannels
por: Jiménez-Dinamarca, Ivanka, et al.
Publicado: (2022)

Effects of enriched-potassium diet on cardiorespiratory outcomes in experimental non-ischemic chronic heart failure
por: Schwarz, Karla G., et al.
Publicado: (2021)

Correction to: Effects of enriched-potassium diet on cardiorespiratory outcomes in experimental non-ischemic chronic heart failure
por: Schwarz, Karla G., et al.
Publicado: (2022)

SARS-CoV-2 spike protein S1 activates Cx43 hemichannels and disturbs intracellular Ca(2+) dynamics
por: Prieto-Villalobos, Juan, et al.
Publicado: (2023)

Ventilatory and Autonomic Regulation in Sleep Apnea Syndrome: A Potential Protective Role for Erythropoietin?
por: Andrade, David C., et al.
Publicado: (2018)

Carotid Body-Mediated Chemoreflex Drive in The Setting of low and High Output Heart Failure
por: Del Rio, Rodrigo, et al.
Publicado: (2017)

Chronic Stress and Gonadectomy Affect the Expression of Cx37, Cx40 and Cx43 in the Spinal Cord
por: Jurić, Marija, et al.
Publicado: (2021)

Comparative Analysis of Cx31 and Cx43 in Differentiation-Competent Rodent Keratinocytes
por: Au, Akina, et al.
Publicado: (2020)

A novel role of Cx43-composed GJIC in PDT phototoxicity: an implication of Cx43 for the enhancement of PDT efficacy
por: Wu, Deng-Pan, et al.
Publicado: (2019)

Vascular dysfunction in HFpEF: Potential role in the development, maintenance, and progression of the disease
por: Saavedra-Alvarez, Andrea, et al.
Publicado: (2022)

Correlations of Differentially Expressed Gap Junction Connexins Cx26, Cx30, Cx32, Cx43 and Cx46 with Breast Cancer Progression and Prognosis
por: Teleki, Ivett, et al.
Publicado: (2014)

Electrophysiology of Single and Aggregate Cx43 Hemichannels
por: Brokamp, Cole, et al.
Publicado: (2012)

Importance of Cx43 for Right Ventricular Function
por: Boengler, Kerstin, et al.
Publicado: (2021)

The Interplay of Cx26, Cx32, Cx37, Cx40, Cx43, Cx45, and Panx1 in Inner-Ear Development of Yotari (dab1−/−) Mice and Humans
por: Lesko, Josip, et al.
Publicado: (2022)

Interaction of Cx43 with Hsc70 regulates G1/S transition through CDK inhibitor p27
por: Hino, Hitoshi, et al.
Publicado: (2015)

Neuron-Glia Crosstalk in the Autonomic Nervous System and Its Possible Role in the Progression of Metabolic Syndrome: A New Hypothesis
por: Del Rio, Rodrigo, et al.
Publicado: (2015)

Effect of connexin 43 inhibition by the mimetic peptide Gap27 on corneal wound healing, inflammation and neovascularization
por: Elbadawy, Hossein Mostafa, et al.
Publicado: (2016)

Opposite Effects of Moderate and Extreme Cx43 Deficiency in Conditional Cx43-Deficient Mice on Angiotensin II-Induced Cardiac Fibrosis
por: Valls-Lacalle, Laura, et al.
Publicado: (2019)

The Cx43 Carboxyl-Terminal Mimetic Peptide αCT1 Protects Endothelial Barrier Function in a ZO1 Binding-Competent Manner
por: Strauss, Randy E., et al.
Publicado: (2021)

Alteration of Cx37, Cx40, Cx43, Cx45, Panx1, and Renin Expression Patterns in Postnatal Kidneys of Dab1-/- (yotari) Mice
por: Lozić, Mirela, et al.
Publicado: (2021)

The Role of Autoantibodies in Arrhythmogenesis
por: Li, Jin
Publicado: (2020)

Regional differences in arrhythmogenesis
por: Short, Ben
Publicado: (2021)

Cardiac Cx43, Cx40 and Cx45 co-assembling: involvement of connexins epitopes in formation of hemichannels and Gap junction channels
por: Desplantez, Thomas
Publicado: (2017)

Altered Expression of Glial Gap Junction Proteins Cx43, Cx30, and Cx47 in the 5XFAD Model of Alzheimer’s Disease
por: Angeli, Stella, et al.
Publicado: (2020)

Relevance of the Carotid Body Chemoreflex in the Progression of Heart Failure
por: Andrade, David C., et al.
Publicado: (2015)

AR Pathway Is Involved in the Regulation of CX43 in Prostate Cancer
por: Chen, Ruibao, et al.
Publicado: (2015)

Aberrant Cx43 Expression and Mislocalization in Metastatic Human Melanomas
por: Alaga, Katanya C., et al.
Publicado: (2017)

Novel Tocolytic Strategy: Modulating Cx43 Activity by S-Nitrosation
por: Barnett, Scott D., et al.
Publicado: (2021)

Src Regulation of Cx43 Phosphorylation and Gap Junction Turnover
por: Solan, Joell L., et al.
Publicado: (2020)

Cx43 phosphorylation sites regulate pancreatic cancer metastasis
por: Solan, Joell L., et al.
Publicado: (2021)

Extracellular Cysteines Are Critical to Form Functional Cx46 Hemichannels
por: Fernández-Olivares, Ainoa, et al.
Publicado: (2022)

Keratitis-Ichthyosis-Deafness syndrome-associated Cx26 mutants produce nonfunctional gap junctions but hyperactive hemichannels when co-expressed with wild type Cx43
por: García, Isaac E., et al.
Publicado: (2015)

Cardiac dynamics: Alternans and arrhythmogenesis
por: Tse, Gary, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_gq4n7te16r1cj9tnol3jslj792